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ADR Term
ADReCS ID
MedDRA Code
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ADR Ontology
ADR Term
Inflammation
ADR ID
BADD_A05823
ADR Hierarchy
08
General disorders and administration site conditions
08.01
General system disorders NEC
08.01.05
Inflammations
08.01.05.007
Inflammation
Description
A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function. [MeSH]
MedDRA Code
10061218
MeSH ID
D007249
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Not Available
Synonym
Inflammation localised | Inflammation localized | Inflammation NOS | Inflammatory reaction | Inflammatory swelling | Inflammation | Exudative inflammation | Inflammations
ADR Related Proteins
Protein Name
UniProt AC
TTD Target ID
Interleukin-1 alpha
P01583
T16340
Interleukin-10
P29456
Not Available
Interleukin-6
P05231
T32578
Interleukin-8
P10145
T22658
Nuclear receptor subfamily 4 group A member 3
Q92570
T93949
Retinol-binding protein 1
P09455
Not Available
Tumor necrosis factor
P01375
T20178
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D01517
Naftifine
-
-
BADD_D01518
Naftifine hydrochloride
-
-
BADD_D01533
Naproxen
-
-
BADD_D01535
Naratriptan
-
-
BADD_D01536
Naratriptan hydrochloride
-
-
BADD_D01550
Nelfinavir mesylate
-
-
BADD_D01557
Nevirapine
-
-
BADD_D01566
Nifedipine
0.000336%
BADD_D01567
Nilotinib
-
-
BADD_D01598
Ofloxacin
-
-
BADD_D01601
Olaparib
0.000533%
BADD_D01629
Osimertinib
-
-
BADD_D01633
Oxaliplatin
-
-
BADD_D01637
Oxcarbazepine
0.000831%
BADD_D01645
Oxycodone
-
-
BADD_D01651
Oxytetracycline hydrochloride
-
-
BADD_D01653
Paclitaxel
0.001598%
BADD_D01654
Palbociclib
-
-
BADD_D01661
Pamidronate disodium
-
-
BADD_D01662
Pamidronic acid
-
-
BADD_D01668
Pantoprazole
0.000241%
BADD_D01687
Pazopanib
0.002131%
BADD_D01710
Penicillin g
-
-
BADD_D01711
Penicillin g benzathine
-
-
BADD_D01765
Phenytoin
-
-
BADD_D01770
Phytonadione
-
-
BADD_D01783
Pirfenidone
0.001359%
BADD_D01788
Plerixafor
-
-
BADD_D01789
Plerixafor octahydrochloride
-
-
BADD_D01790
Podofilox
-
-
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